Temporal arteritis

M13_TEMPARTERIT

temporal arteritis: Giant cell arteritis (GCA) is a large vessel vasculitis predominantly involving the arteries originating from the aortic arch and especially the extracranial branches of the carotid arteries.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 M31.5
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 M31.5
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

819

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

819

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Check minimum number of events None

819

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Include endpoints None

819

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M13_TEMPARTERIT

Extra metadata

Level in the ICD hierarchy 5
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M31
Name in latin Arteritis gigantocellularis cum polymyalgia reumatica

Summary Statistics

Key figures

All Female Male
Number of individuals 819 497 322
Unadjusted prevalence (%) 0.23 0.25 0.20
Mean age at first event (years) 68.49 67.62 69.82

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.26 [1.60, 6.63] 1.2e-3 134
15 years 0.01 1.60 [0.98, 2.61] 5.8e-2 51
5 years 0.00 3.09 [2.10, 4.56] 1.3e-8 48
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: M13_TEMPARTERIT – Temporal arteritis
GWS hits:

Survival analyses between endpoints

Plot

before Temporal arteritis
after Temporal arteritis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Temporal arteritis