Keratoconus

H7_CORNEALDEFORM

No definition available.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 H18.6
Hospital discharge: ICD-9 3716
Hospital discharge: ICD-8 37103
Cause of death: ICD-10 H18.6
Cause of death: ICD-9 3716
Cause of death: ICD-8 37103

573

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

573

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Check minimum number of events None

573

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Include endpoints None

573

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H7_CORNEALDEFORM

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H18
Name in latin Keratoconus

Summary Statistics

Key figures

All Female Male
Number of individuals 573 240 333
Unadjusted prevalence (%) 0.16 0.12 0.21
Mean age at first event (years) 43.43 45.64 41.83

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.62 [0.65, 4.00] 3.0e-1 21
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: H7_CORNEALDEFORM – Keratoconus
GWS hits: 4

Survival analyses between endpoints

Plot

before Keratoconus
after Keratoconus

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