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Other disorders of cornea

DOID EFO MESH SNOMED PheWeb

H7_CORNEALOTH

corneal disease: A non-neoplastic or neoplastic disorder that affects the cornea. Representative examples include keratitis, bullous keratopathy, and squamous cell carcinoma.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 H18
Cause of death: ICD-10 H18

2180

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

2180

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Check minimum number of events None

2180

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Include endpoints

2262

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H7_CORNEALOTH

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H15-H22
Name in latin Aliae morbositates corneae

Similar endpoints

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List of similar endpoints to Other disorders of cornea based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 2262 1277 985
Unadjusted prevalence (%) 0.64 0.64 0.63
Mean age at first event (years) 54.09 55.09 52.80

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.11 [1.17, 3.80] 1.4e-2 171
15 years 0.01 1.37 [0.87, 2.16] 1.8e-1 74
5 years 0.00 3.38 [2.33, 4.91] 1.3e-10 66
1 year 0.00 2.85 [1.49, 5.46] 1.6e-3 11

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_CORNEALOTH – Other disorders of cornea
GWS hits: 7

Survival analyses between endpoints

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Plot

before Other disorders of cornea
after Other disorders of cornea

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Drugs most likely to be purchased after Other disorders of cornea

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