Conductive and sensorineural hearing loss

H8_CONSENHEARINGLOSS

sensorineural hearing loss: Hearing loss in which the root cause lies in the inner ear or sensory organ (cochlea and associated structures) or the vestibulocochlear nerve (cranial nerve VIII).

Endpoint definition

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FinnGen phenotype data

356077 individuals

Apply sex-specific rule None

356077

Check conditions None

356077

Filter registries None

Check pre-conditions, main-only, mode, ICD version None

Check minimum number of events None

Include endpoints

H8_HL_CON_NAS

H8_HL_SEN_NAS

H8_HL_MIX_NAS

31620

H8_CONSENHEARINGLOSS

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

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Or the full data table

Similar endpoints

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List of similar endpoints to Conductive and sensorineural hearing loss based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	31620	15047	16573
Unadjusted prevalence (%)	8.89	7.58	10.53
Mean age at first event (years)	63.19	60.95	65.22

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	1.60 [1.41, 1.82]	1.3e-12	4160
15 years	0.01	1.03 [0.91, 1.17]	6.0e-1	2051
5 years	0.00	1.92 [1.74, 2.11]	4.8e-39	1349
1 year	0.00	2.64 [2.29, 3.05]	6.4e-41	360

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H8_CONSENHEARINGLOSS – Conductive and sensorineural hearing loss
GWS hits:

Survival analyses between endpoints

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Plot

before Conductive and sensorineural hearing loss
after Conductive and sensorineural hearing loss

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Table

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Drugs most likely to be purchased after Conductive and sensorineural hearing loss

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≡ Risteys

R8

R7

R6

R5

R4

R3