Vestibular neuronitis

H8_VESTIBNEUR

vestibular neuronitis: Idiopathic inflammation of the vestibular nerve, characterized clinically by the acute or subacute onset of vertigo; nausea; and imbalance. The cochlear nerve is typically spared and hearing loss and tinnitus do not usually occur. Symptoms usually resolve over a period of days to weeks. (Adams et al., Principles of Neurology, 6th ed, p304)

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 H81.2
Hospital discharge: ICD-9 3861
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 H81.2
Cause of death: ICD-9 3861
Cause of death: ICD-8 $!$

2149

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

2149

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Check minimum number of events None

2149

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Include endpoints None

2149

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H8_VESTIBNEUR

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H81
Name in latin Neuronitis vestibularis

Summary Statistics

Key figures

All Female Male
Number of individuals 2149 1215 934
Unadjusted prevalence (%) 0.60 0.61 0.59
Mean age at first event (years) 54.28 52.95 56.02

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.52 [0.98, 2.38] 6.4e-2 139
15 years 0.01 0.92 [0.60, 1.43] 7.2e-1 64
5 years 0.00 1.53 [0.95, 2.46] 8.1e-2 31
1 year 0.00 2.66 [1.33, 5.29] 5.4e-3 10

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: H8_VESTIBNEUR – Vestibular neuronitis
GWS hits: 1

Survival analyses between endpoints

Plot

before Vestibular neuronitis
after Vestibular neuronitis

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Drugs most likely to be purchased after Vestibular neuronitis