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Other/unspecified disorders of vestibular function

DOID EFO MESH PheWeb

H8_VESTIFUNCNAS

vestibular disease: Pathological processes of the vestibular labyrinth which contains part of the balancing apparatus. Patients with vestibular diseases show instability and are at risk of frequent falls. [database_cross_reference: MESH:D015837]

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 H81.8, H81.9
Hospital discharge: ICD-9 386[8-9]
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 H81.8, H81.9
Cause of death: ICD-9 386[8-9]
Cause of death: ICD-8 $!$

1234

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

801

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Check minimum number of events None

801

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Include endpoints None

801

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H8_VESTIFUNCNAS

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 801 482 319
Unadjusted prevalence (%) 0.23 0.24 0.20
Mean age at first event (years) 59.38 58.52 60.68

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.30 [0.75, 2.23] 3.5e-1 96
15 years 0.01 0.79 [0.46, 1.37] 4.0e-1 42
5 years 0.00 2.02 [1.22, 3.34] 6.2e-3 28
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H8_VESTIFUNCNAS – Other/unspecified disorders of vestibular function
GWS hits:

Survival analyses between endpoints

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Plot

before Other/unspecified disorders of vestibular function
after Other/unspecified disorders of vestibular function

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other/unspecified disorders of vestibular function

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