AV-block

I9_AVBLOCK

No definition available.

Endpoint definition

FinnGen phenotype data

356077 individuals

diagram downward connector

Apply sex-specific rule None

356077

diagram downward connector

Check conditions None

356077

diagram downward connector
diagram bullet

Filter registries

Hospital Discharge: ICD-10 I44.0, I44.1, I44.2, I44.3
Hospital discharge: ICD-9 426[0-1]
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 I44.0, I44.1, I44.2, I44.3
Cause of death: ICD-9 426[0-1]
Cause of death: ICD-8 $!$

5002

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

4983

diagram downward connector

Check minimum number of events None

4983

diagram downward connector

Include endpoints None

4983

diagram downward connector
I9_AVBLOCK

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 4983 1570 3413
Unadjusted prevalence (%) 1.40 0.79 2.17
Mean age at first event (years) 69.57 66.76 70.86

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.53 [1.79, 3.59] 1.8e-7 1232
15 years 0.01 1.07 [0.81, 1.43] 6.3e-1 420
5 years 0.00 2.63 [2.19, 3.16] 6.0e-25 469
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: I9_AVBLOCK – AV-block
GWS hits: 3

Survival analyses between endpoints

Plot

before AV-block
after AV-block

loading spinner Loading survival analyses plot