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Cardiovascular diseases (excluding rheumatic etc)

DOID EFO MESH SNOMED PheWeb

FG_CVD

cardiovascular disease: A disease involving the cardiovascular system.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries None

0

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Check pre-conditions, main-only, mode, ICD version None

0

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Check minimum number of events None

0

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Include endpoints

180065

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FG_CVD

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 180065 88111 91954
Unadjusted prevalence (%) 50.61 44.41 58.43
Mean age at first event (years) 52.73 50.22 55.13

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 4.50 [4.23, 4.78] <1e-100 30997
15 years 0.01 2.94 [2.73, 3.17] <1e-100 13407
5 years 0.00 4.37 [4.01, 4.76] <1e-100 5810
1 year 0.00 19.91 [16.94, 23.40] <1e-100 4107

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: FG_CVD – Cardiovascular diseases (excluding rheumatic etc)
GWS hits: 52

Survival analyses between endpoints

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Plot

before Cardiovascular diseases (excluding rheumatic etc)
after Cardiovascular diseases (excluding rheumatic etc)

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Cardiovascular diseases (excluding rheumatic etc)

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