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Coronary artery bypass grafting

DOID EFO MESH SNOMED PheWeb

I9_CABG

Coronary Vasospasm: Sudden coronary artery smooth muscle contraction leading to lumen constriction and decreased blood flow.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Operations: NOMESCO codes ^FNA|^FNB|^FNC|^FND|^FNE
Operations: Finnish Hospital League codes ^5311$|^5312$|^5313$|^5314$|^5315$
Operations: Heart Patient codes v1 ^11$|^25$|^111$|^112$|^113$|^119$
Operations: Heart Patient codes v2 ^AA1|^AA2|^AA3|^AAX

77509

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Check pre-conditions, main-only, mode, ICD version None

10221

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Check minimum number of events None

10221

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Include endpoints None

10221

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I9_CABG

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 10221 1673 8548
Unadjusted prevalence (%) 2.87 0.84 5.43
Mean age at first event (years) 64.52 66.48 64.14

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.81 [1.55, 2.11] 4.8e-14 3441
15 years 0.01 1.44 [1.27, 1.63] 1.1e-8 1876
5 years 0.00 1.64 [1.46, 1.85] 1.2e-16 614
1 year 0.00 3.91 [3.33, 4.60] 2.5e-62 260

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_CABG – Coronary artery bypass grafting
GWS hits: 58

Survival analyses between endpoints

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Plot

before Coronary artery bypass grafting
after Coronary artery bypass grafting

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Coronary artery bypass grafting

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