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Ischemic heart diseases

DOID EFO MESH SNOMED PheWeb

I9_ISCHHEART

coronary thrombosis: Coagulation of blood in any of the coronary vessels. The presence of a blood clot (thrombus) often leads to myocardial infarction.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 I20-I25
Cause of death: ICD-10 I20-I25

55100

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

55100

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Check minimum number of events None

55100

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Include endpoints

58690

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I9_ISCHHEART

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Similar endpoints

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Summary Statistics

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Key figures

All Female Male
Number of individuals 58690 19590 39100
Unadjusted prevalence (%) 16.50 9.87 24.85
Mean age at first event (years) 64.41 65.38 63.93

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 3.73 [3.44, 4.04] <1e-100 18046
15 years 0.01 2.26 [2.09, 2.44] 1.6e-95 6811
5 years 0.00 3.63 [3.37, 3.89] <1e-100 3689
1 year 0.01 27.66 [24.81, 30.83] <1e-100 5221

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_ISCHHEART – Ischemic heart diseases
GWS hits:

Survival analyses between endpoints

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Plot

before Ischemic heart diseases
after Ischemic heart diseases

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Ischemic heart diseases

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