Restrictive cardiomyopathy

I9_CARDMYORESTR

restrictive cardiomyopathy: A type of heart disorder referring to the inability of the ventricles to fill with blood because the myocardium (heart muscle) stiffens and looses its flexibility. Causes include replacement of the myocardium with scar tissue, abnormal cellular infiltration of the myocardium, or deposition of a substance (e.g., amyloid) in the myocardium.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 I42.5
Hospital discharge: ICD-9 4250A
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 I42.5
Cause of death: ICD-9 4250A
Cause of death: ICD-8 $!$

92

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

92

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Check minimum number of events None

92

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Include endpoints None

92

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I9_CARDMYORESTR

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF2
Parent code in ICD-10 I42
Name in latin Cardiomyopathia restrictiva

Summary Statistics

Key figures

All Female Male
Number of individuals 92 39 53
Unadjusted prevalence (%) 0.03 0.02 0.03
Mean age at first event (years) 60.25 62.37 58.70

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: I9_CARDMYORESTR – Restrictive cardiomyopathy
GWS hits:

Survival analyses between endpoints

Plot

before Restrictive cardiomyopathy
after Restrictive cardiomyopathy

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Restrictive cardiomyopathy