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Cardiomyopathies, Primary/intrinsic

DOID EFO MESH SNOMED PheWeb

I9_CARDMPRI

cardiomyopathy: A disease of the heart muscle or myocardium proper. Cardiomyopathies may be classified as either primary or secondary, on the basis of etiology, or on the pathophysiology of the lesion: hypertrophic, dilated, or restrictive.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 I42.0, I42.1, I42.3, I42.4, I42.5
Hospital discharge: ICD-9 4250A|4254A
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 I42.0, I42.1, I42.3, I42.4, I42.5
Cause of death: ICD-9 4250A|4254A
Cause of death: ICD-8 $!$

3803

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

3803

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Check minimum number of events None

3803

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Include endpoints None

3803

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I9_CARDMPRI

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 3803 1029 2774
Unadjusted prevalence (%) 1.07 0.52 1.76
Mean age at first event (years) 59.95 57.61 60.82

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 5.22 [3.80, 7.17] 2.1e-24 922
15 years 0.02 2.66 [2.00, 3.54] 2.2e-11 391
5 years 0.01 4.90 [3.91, 6.15] 6.7e-43 281
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_CARDMPRI – Cardiomyopathies, Primary/intrinsic
GWS hits:

Survival analyses between endpoints

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Plot

before Cardiomyopathies, Primary/intrinsic
after Cardiomyopathies, Primary/intrinsic

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Cardiomyopathies, Primary/intrinsic

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