Calcific aortic valvular stenosis, diagnosis (helper)

I9_CAVS_DX

No definition available.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 I35.0, I35.2
Hospital discharge: ICD-9 4241[BC]
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 I35.0, I35.2
Cause of death: ICD-9 4241[BC]
Cause of death: ICD-8 $!$

8275

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

8275

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Check minimum number of events None

8275

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Include endpoints None

8275

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I9_CAVS_DX

Extra metadata

First used in FinnGen datafreeze DF6v3

Summary Statistics

Key figures

All Female Male
Number of individuals 8275 3106 5169
Unadjusted prevalence (%) 2.33 1.57 3.28
Mean age at first event (years) 70.92 72.08 70.23

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 3.55 [2.96, 4.26] 4.9e-42 2201
15 years 0.01 1.48 [1.23, 1.79] 3.7e-5 805
5 years 0.00 3.19 [2.77, 3.68] 8.0e-57 752
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: I9_CAVS_DX – Calcific aortic valvular stenosis, diagnosis (helper)
GWS hits:

Survival analyses between endpoints

Plot

before Calcific aortic valvular stenosis, diagnosis (helper)
after Calcific aortic valvular stenosis, diagnosis (helper)

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Drugs most likely to be purchased after Calcific aortic valvular stenosis, diagnosis (helper)