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Calcific aortic valvular stenosis, including rheumatic fever

PheWeb

I9_CAVS_RHEU

No definition available.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 I06.0, I06.2, I35.0, I35.2
Hospital discharge: ICD-9 3950A|3952A|4241[BC]
Hospital discharge: ICD-8 39500|39502
Cause of death: ICD-10 I06.0, I06.2, I35.0, I35.2
Cause of death: ICD-9 3950A|3952A|4241[BC]
Cause of death: ICD-8 39500|39502

8333

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

8333

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Check minimum number of events None

8333

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Include endpoints None

8333

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I9_CAVS_RHEU

Extra metadata

First used in FinnGen datafreeze DF6v3

Summary Statistics

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Key figures

All Female Male
Number of individuals 8333 3135 5198
Unadjusted prevalence (%) 2.34 1.58 3.30
Mean age at first event (years) 70.74 71.84 70.07

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 3.32 [2.54, 4.35] 2.2e-18 2225
15 years 0.01 1.53 [1.25, 1.86] 2.6e-5 812
5 years 0.00 3.32 [2.88, 3.83] 2.6e-60 758
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_CAVS_RHEU – Calcific aortic valvular stenosis, including rheumatic fever
GWS hits:

Survival analyses between endpoints

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Plot

before Calcific aortic valvular stenosis, including rheumatic fever
after Calcific aortic valvular stenosis, including rheumatic fever

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Calcific aortic valvular stenosis, including rheumatic fever

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