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Endocarditis

DOID EFO MESH SNOMED PheWeb

I9_ENDOCARD

endocarditis: Inflammation of the endocardium.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 I33, I38, I39*
Hospital discharge: ICD-9 421|4249|0932A
Hospital discharge: ICD-8 421
Cause of death: ICD-10 I33, I38, I39*
Cause of death: ICD-9 421|4249|0932A
Cause of death: ICD-8 421

891

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

876

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Check minimum number of events None

876

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Include endpoints None

876

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I9_ENDOCARD

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF6

Summary Statistics

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Key figures

All Female Male
Number of individuals 876 258 618
Unadjusted prevalence (%) 0.25 0.13 0.39
Mean age at first event (years) 59.21 56.04 60.53

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.12 7.92 [5.36, 11.71] 2.8e-25 233
15 years 0.02 2.56 [1.69, 3.88] 8.2e-6 65
5 years 0.01 4.58 [2.71, 7.75] 1.4e-8 69
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_ENDOCARD – Endocarditis
GWS hits: 1

Survival analyses between endpoints

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Plot

before Endocarditis
after Endocarditis

loading spinner Loading survival analyses plot