Left bundle-branch block

I9_LBBB

No definition available.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 I44.4, I44.5, I44.6, I44.7
Hospital discharge: ICD-9 426[2-3]
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 I44.4, I44.5, I44.6, I44.7
Cause of death: ICD-9 426[2-3]
Cause of death: ICD-8 $!$

1705

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1705

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Check minimum number of events None

1705

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Include endpoints None

1705

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I9_LBBB

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 1705 850 855
Unadjusted prevalence (%) 0.48 0.43 0.54
Mean age at first event (years) 66.24 64.48 68.00

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 5.02 [3.53, 7.12] 2.0e-19 252
15 years 0.01 1.99 [1.35, 2.93] 4.7e-4 94
5 years 0.01 4.16 [3.08, 5.64] 2.7e-20 100
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: I9_LBBB – Left bundle-branch block
GWS hits: 2

Survival analyses between endpoints

Plot

before Left bundle-branch block
after Left bundle-branch block

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Left bundle-branch block