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Nonischemic cardiomyopathy

DOID EFO MESH SNOMED PheWeb

I9_NONISCHCARDMYOP_STRICT

dilated cardiomyopathy: Cardiomyopathy which is characterized by dilation and contractile dysfunction of the left and right ventricles. It may be idiopathic, or it may result from a myocardial infarction, myocardial infection, or alcohol abuse. It is a cause of congestive heart failure.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions

not I9_IHD
and not I9_HYPERTROCARDMYOP

296984

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Filter registries

Hospital Discharge: ICD-10 I42.0, I51.1
Hospital discharge: ICD-9 4281
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 I42.0, I51.1
Cause of death: ICD-9 4281
Cause of death: ICD-8 $!$

1534

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1534

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Check minimum number of events None

1534

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Include endpoints None

1534

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I9_NONISCHCARDMYOP_STRICT

Extra metadata

First used in FinnGen datafreeze DF3

Summary Statistics

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Key figures

All Female Male
Number of individuals 1534 440 1094
Unadjusted prevalence (%) 0.43 0.22 0.70
Mean age at first event (years) 57.55 56.15 58.11

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 3.61 [1.66, 7.84] 1.2e-3 232
15 years 0.02 2.19 [1.27, 3.79] 5.1e-3 98
5 years 0.00 3.81 [2.52, 5.76] 2.4e-10 62
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_NONISCHCARDMYOP_STRICT – Nonischemic cardiomyopathy
GWS hits: 4

Survival analyses between endpoints

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Plot

before Nonischemic cardiomyopathy
after Nonischemic cardiomyopathy

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Nonischemic cardiomyopathy

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