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Diseases of vocal cords and larynx+other diseases of upper respiratory tract, no elsewhere classified

DOID EFO MESH SNOMED PheWeb

J10_VOCALLARYNX

laryngeal disease: A non-neoplastic or neoplastic disorder that affects the larynx. Representative examples include laryngitis, vocal cord polyp, squamous papilloma, and carcinoma. [database_cross_reference: NCIT:P378]

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 J34, J38, J39
Hospital discharge: ICD-9 478
Hospital discharge: ICD-8 508
Hospital discharge: excluded ICD-8 50803
Cause of death: ICD-10 J34, J38, J39
Cause of death: ICD-9 478
Cause of death: ICD-8 508
Cause of death: excluded ICD-8 50803

17933

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

17913

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Check minimum number of events None

17913

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Include endpoints None

17913

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J10_VOCALLARYNX

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Similar endpoints

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Summary Statistics

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Key figures

All Female Male
Number of individuals 17913 8927 8986
Unadjusted prevalence (%) 5.03 4.50 5.71
Mean age at first event (years) 48.02 46.50 49.53

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.27 [1.02, 1.58] 3.1e-2 1244
15 years 0.01 0.86 [0.70, 1.06] 1.5e-1 509
5 years 0.00 1.91 [1.58, 2.30] 1.5e-11 290
1 year 0.00 5.85 [4.72, 7.27] 9.7e-58 163

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: J10_VOCALLARYNX – Diseases of vocal cords and larynx+other diseases of upper respiratory tract, no elsewhere classified
GWS hits: 1

Survival analyses between endpoints

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Plot

before Diseases of vocal cords and larynx+other diseases of upper respiratory tract, no elsewhere classified
after Diseases of vocal cords and larynx+other diseases of upper respiratory tract, no elsewhere classified

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Drugs most likely to be purchased after Diseases of vocal cords and larynx+other diseases of upper respiratory tract, no elsewhere classified

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