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Achalasia of cardia

DOID MESH PheWeb

K11_ACHAL

No definition available.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 K22.0
Hospital discharge: ICD-9 5300
Hospital discharge: ICD-8 5300
Cause of death: ICD-10 K22.0
Cause of death: ICD-9 5300
Cause of death: ICD-8 5300

470

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

470

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Check minimum number of events None

470

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Include endpoints None

470

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K11_ACHAL

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 K22
Name in latin Achalasia cardiae

Summary Statistics

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Key figures

All Female Male
Number of individuals 470 232 238
Unadjusted prevalence (%) 0.13 0.12 0.15
Mean age at first event (years) 50.67 47.08 54.17

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.21 [1.03, 4.76] 4.3e-2 66
15 years 0.01 1.39 [0.76, 2.56] 2.9e-1 26
5 years 0.00 2.94 [1.65, 5.24] 2.6e-4 19
1 year 0.00 9.82 [5.03, 19.18] 2.3e-11 12

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: K11_ACHAL – Achalasia of cardia
GWS hits: 1

Survival analyses between endpoints

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Plot

before Achalasia of cardia
after Achalasia of cardia

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Drugs most likely to be purchased after Achalasia of cardia

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