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Cholangitis (primary sclerosing, PSC), with reimbursement 202

DOID EFO MESH SNOMED PheWeb

K11_CHOLANGI_STRICT

sclerosing cholangitis: A chronic, autoimmune inflammatory liver disorder characterized by narrowing and scarring of the lumen of the bile ducts. It is often seen in patients with ulcerative colitis. Signs and symptoms include jaundice, fatigue, and malabsorption. It may lead to cirrhosis and liver failure.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions

K11_REIMB_202

19458

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Filter registries

Hospital Discharge: ICD-10 K83.0
Hospital discharge: ICD-9 5761
Hospital discharge: ICD-8 5750[4-5]
Cause of death: ICD-10 K83.0
Cause of death: ICD-9 5761
Cause of death: ICD-8 5750[4-5]

440

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

440

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Check minimum number of events None

440

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Include endpoints None

440

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K11_CHOLANGI_STRICT

Extra metadata

First used in FinnGen datafreeze DF3
Parent code in ICD-10 K83
Name in latin Cholangitis

Summary Statistics

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Key figures

All Female Male
Number of individuals 440 243 197
Unadjusted prevalence (%) 0.12 0.12 0.13
Mean age at first event (years) 44.09 46.68 40.89

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 4.20 [1.31, 13.45] 1.6e-2 28
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: K11_CHOLANGI_STRICT – Cholangitis (primary sclerosing, PSC), with reimbursement 202
GWS hits: 1

Survival analyses between endpoints

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Plot

before Cholangitis (primary sclerosing, PSC), with reimbursement 202
after Cholangitis (primary sclerosing, PSC), with reimbursement 202

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Cholangitis (primary sclerosing, PSC), with reimbursement 202

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