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Chronic gastritis

DOID EFO MESH SNOMED PheWeb

K11_CHRONGASTR

atrophic gastritis: GASTRITIS with atrophy of the GASTRIC MUCOSA, the GASTRIC PARIETAL CELLS, and the mucosal glands leading to ACHLORHYDRIA. Atrophic gastritis usually progresses from chronic gastritis.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 K29.3, K29.4, K29.5
Hospital discharge: ICD-9 5351|5354
Hospital discharge: ICD-8 53503
Cause of death: ICD-10 K29.3, K29.4, K29.5
Cause of death: ICD-9 5351|5354
Cause of death: ICD-8 53503

8966

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

8966

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Check minimum number of events None

8966

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Include endpoints None

8966

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K11_CHRONGASTR

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 8966 4983 3983
Unadjusted prevalence (%) 2.52 2.51 2.53
Mean age at first event (years) 60.27 58.16 62.91

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.00 [1.56, 2.58] 7.0e-8 1540
15 years 0.01 1.33 [1.09, 1.61] 4.4e-3 726
5 years 0.00 2.45 [2.07, 2.89] 1.7e-25 455
1 year 0.00 4.60 [3.74, 5.67] 1.2e-46 164

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: K11_CHRONGASTR – Chronic gastritis
GWS hits:

Survival analyses between endpoints

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Plot

before Chronic gastritis
after Chronic gastritis

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Drugs most likely to be purchased after Chronic gastritis

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