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Disorders of oesophagus in diseases classified elsewhere

DOID EFO MESH SNOMED PheWeb

K11_DISOESINOTH

esophageal disease: A non-neoplastic or neoplastic disorder that affects the esophagus. Representative examples of non-neoplastic disorders include esophagitis and esophageal ulcer. Representative examples of neoplastic disorders include carcinomas, lymphomas, and melanomas.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 K23*
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 K23*
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

470

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

470

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Check minimum number of events None

470

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Include endpoints None

470

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K11_DISOESINOTH

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 470 226 244
Unadjusted prevalence (%) 0.13 0.11 0.16
Mean age at first event (years) 63.35 60.47 66.02

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.22 14.74 [9.78, 22.22] 9.1e-38 122
15 years 0.02 3.37 [2.14, 5.30] 1.5e-7 27
5 years 0.01 8.54 [5.60, 13.03] 2.7e-23 39
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: K11_DISOESINOTH – Disorders of oesophagus in diseases classified elsewhere
GWS hits: 1

Survival analyses between endpoints

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Plot

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Drugs most likely to be purchased after Disorders of oesophagus in diseases classified elsewhere

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