Gastroduodenal ulcer

K11_GASTRODUOULC

gastric ulcer: An ulcerated lesion in the mucosal surface of the stomach. It may progress to involve the deeper layers of the gastric wall. [ NCIT:P378 ]

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 K25, K26, K27, K28
Cause of death: ICD-10 K25, K26, K27, K28

7336

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

7336

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Check minimum number of events None

7336

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Include endpoints

8534

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K11_GASTRODUOULC

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 8534 3271 5263
Unadjusted prevalence (%) 2.40 1.65 3.34
Mean age at first event (years) 61.37 59.63 62.46

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 2.74 [2.23, 3.36] 2.7e-22 2593
15 years 0.01 1.43 [1.21, 1.68] 2.3e-5 955
5 years 0.00 3.20 [2.79, 3.66] 3.3e-64 720
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: K11_GASTRODUOULC – Gastroduodenal ulcer
GWS hits: 3

Survival analyses between endpoints

Plot

before Gastroduodenal ulcer
after Gastroduodenal ulcer

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Gastroduodenal ulcer