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Other diseases of oesophagus

DOID EFO MESH SNOMED PheWeb

K11_OTHDISOES

esophageal disease: A non-neoplastic or neoplastic disorder that affects the esophagus. Representative examples of non-neoplastic disorders include esophagitis and esophageal ulcer. Representative examples of neoplastic disorders include carcinomas, lymphomas, and melanomas.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 K22.4, K22.5, K22.6, K22.7, K22.8, K22.9
Hospital discharge: ICD-9 530[5-9]
Hospital discharge: ICD-8 5302|5309
Hospital discharge: excluded ICD-10 K22.7
Cause of death: ICD-10 K22.4, K22.5, K22.6, K22.7, K22.8, K22.9
Cause of death: ICD-9 530[5-9]
Cause of death: ICD-8 5302|5309

2740

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

2718

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Check minimum number of events None

2718

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Include endpoints None

2718

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K11_OTHDISOES

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 2718 1174 1544
Unadjusted prevalence (%) 0.76 0.59 0.98
Mean age at first event (years) 54.54 52.74 55.90

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.50 [1.02, 2.19] 4.0e-2 524
15 years 0.01 0.95 [0.71, 1.27] 7.1e-1 215
5 years 0.00 1.98 [1.53, 2.55] 1.9e-7 136
1 year 0.00 4.20 [3.01, 5.87] 3.8e-17 53

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: K11_OTHDISOES – Other diseases of oesophagus
GWS hits:

Survival analyses between endpoints

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Plot

before Other diseases of oesophagus
after Other diseases of oesophagus

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other diseases of oesophagus

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