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Schizophrenia or delusion

DOID EFO MESH SNOMED PheWeb

KRA_PSY_SCHIZODEL

schizophrenia: A major psychotic disorder characterized by abnormalities in the perception or expression of reality. It affects the cognitive and psychomotor functions. Common clinical signs and symptoms include delusions, hallucinations, disorganized thinking, and retreat from reality.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 F20-F29
Hospital discharge: ICD-9 295|29[7-8]
Hospital discharge: ICD-8 295|297|298[1-9]|299
Cause of death: ICD-10 F20-F29
Cause of death: ICD-9 295|29[7-8]
Cause of death: ICD-8 295|297|298[1-9]|299

12998

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

12878

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Check minimum number of events None

12878

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Include endpoints None

12878

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KRA_PSY_SCHIZODEL

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 12878 6625 6253
Unadjusted prevalence (%) 3.62 3.34 3.97
Mean age at first event (years) 34.89 35.94 33.78

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 2.71 [2.17, 3.39] 1.6e-18 1146
15 years 0.01 1.77 [1.44, 2.16] 3.1e-8 444
5 years 0.00 3.11 [2.59, 3.72] 9.2e-35 226
1 year 0.00 6.20 [4.83, 7.95] 1.1e-46 88

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: KRA_PSY_SCHIZODEL – Schizophrenia or delusion
GWS hits:

Survival analyses between endpoints

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Plot

before Schizophrenia or delusion
after Schizophrenia or delusion

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Schizophrenia or delusion

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