≡ Risteys
R8

Documentation Changelog GitHub Contact & Feedback

Allergic urticaria

DOID EFO MESH SNOMED PheWeb

L12_URTICA_ALLERG

allergic urticaria: commonly referred to as hives, is a kind of skin rash notable for pale red, raised, itchy bumps. Hives may cause a burning or stinging sensation. Histamine and other proinflammatory substances are released from mast cells in the skin and tissues in response to the binding of allergen-bound IgE antibodies to high-affinity cell surface receptors. Basophils and other inflammatory cells are also seen to release histamine and other mediators, and are thought to play an important role, especially in chronic urticarial diseases.

Endpoint definition

↥
FinnGen phenotype data

356077 individuals

diagram downward connector

Apply sex-specific rule None

356077

diagram downward connector

Check conditions None

356077

diagram downward connector
diagram bullet

Filter registries

Hospital Discharge: ICD-10 L50.0
Hospital discharge: ICD-9 7080
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 L50.0
Cause of death: ICD-9 7080
Cause of death: ICD-8 $!$

2283

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

2199

diagram downward connector

Check minimum number of events None

2199

diagram downward connector

Include endpoints None

2199

diagram downward connector
L12_URTICA_ALLERG

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L50
Name in latin Urticaria allergica

Summary Statistics

↥

Key figures

All Female Male
Number of individuals 2199 1557 642
Unadjusted prevalence (%) 0.62 0.78 0.41
Mean age at first event (years) 41.68 40.99 43.36

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.41 [0.51, 3.84] 5.1e-1 124
15 years 0.01 1.02 [0.42, 2.48] 9.6e-1 52
5 years 0.00 2.56 [1.33, 4.96] 5.1e-3 36
1 year 0.00 4.83 [2.20, 10.60] 8.7e-5 12

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: L12_URTICA_ALLERG – Allergic urticaria
GWS hits: 1

Survival analyses between endpoints

↥

Plot

before Allergic urticaria
after Allergic urticaria

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Allergic urticaria

↥