Urticaria and erythema

L12_URTICARIAERYTHEMA

urticaria: A vascular reaction of the skin characterized by erythema and wheal formation due to localized increase of vascular permeability. The causative mechanism may be allergy, infection, or stress.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 L50-L54
Cause of death: ICD-10 L50-L54

9443

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

9443

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Check minimum number of events None

9443

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L12_URTICARIAERYTHEMA

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 11677 8130 3547
Unadjusted prevalence (%) 3.28 4.10 2.25
Mean age at first event (years) 42.04 41.31 43.71

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.67 [1.28, 2.18] 1.8e-4 690
15 years 0.01 1.21 [0.96, 1.51] 1.1e-1 289
5 years 0.00 2.53 [2.06, 3.10] 1.0e-18 171
1 year 0.00 5.55 [4.19, 7.36] 7.0e-33 69

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: L12_URTICARIAERYTHEMA – Urticaria and erythema
GWS hits:

Survival analyses between endpoints

Plot

before Urticaria and erythema
after Urticaria and erythema

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Drugs most likely to be purchased after Urticaria and erythema