Urticaria

L12_URTICARIA

urticaria: A vascular reaction of the skin characterized by erythema and wheal formation due to localized increase of vascular permeability. The causative mechanism may be allergy, infection, or stress.

Endpoint definition

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FinnGen phenotype data

356077 individuals

Apply sex-specific rule None

356077

Check conditions None

356077

Filter registries None

Check pre-conditions, main-only, mode, ICD version None

Check minimum number of events None

Include endpoints

L12_URTICA_ALLERG

L12_URTICA_IDIOPAT

L12_URTICA_COLDHEAT

L12_URTICA_DERTMATOG

L12_URTICA_VIBR

L12_URTICA_CHOLINERG

L12_URTIGA_CONTACT

L12_URTICA_NAS

9386

L12_URTICARIA

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

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Similar endpoints

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List of similar endpoints to Urticaria based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

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Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	9386	6697	2689
Unadjusted prevalence (%)	2.64	3.38	1.71
Mean age at first event (years)	40.97	40.53	42.06

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	1.73 [1.33, 2.26]	5.5e-5	444
15 years	0.01	1.09 [0.83, 1.42]	5.5e-1	183
5 years	0.00	2.21 [1.67, 2.92]	2.4e-8	113
1 year	0.00	4.34 [2.98, 6.32]	1.8e-14	40

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_URTICARIA – Urticaria
GWS hits: 5

Survival analyses between endpoints

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Plot

before Urticaria
after Urticaria

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Table

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Drugs most likely to be purchased after Urticaria

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≡ Risteys

R8

R7

R6

R5

R4

R3