Other and unspecified urticaria

L12_URTICA_NAS

urticaria: A vascular reaction of the skin characterized by erythema and wheal formation due to localized increase of vascular permeability. The causative mechanism may be allergy, infection, or stress.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 L50.8, L50.9
Hospital discharge: ICD-9 708[8-9]
Hospital discharge: ICD-8 708
Cause of death: ICD-10 L50.8, L50.9
Cause of death: ICD-9 708[8-9]
Cause of death: ICD-8 708

6183

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

5898

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Check minimum number of events None

5898

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Include endpoints None

5898

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L12_URTICA_NAS

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 5898 4194 1704
Unadjusted prevalence (%) 1.66 2.11 1.08
Mean age at first event (years) 40.01 39.89 40.31

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.68 [1.15, 2.45] 7.1e-3 285
15 years 0.01 1.16 [0.83, 1.62] 3.9e-1 120
5 years 0.00 2.20 [1.57, 3.08] 4.1e-6 65
1 year 0.00 4.22 [2.63, 6.77] 2.4e-9 23

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_URTICA_NAS – Other and unspecified urticaria
GWS hits: 3

Survival analyses between endpoints

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Plot

before Other and unspecified urticaria
after Other and unspecified urticaria

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other and unspecified urticaria

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