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Vibratory urticaria

DOID EFO MESH SNOMED PheWeb

L12_URTICA_VIBR

vibratory urticaria: This very rare form of angioedema develops in reply to contact with vibration. In vibratory angioedema, symptoms develop within two to five minutes after contact with vibration and dissolve after about an hour. Patients with this disorder do not suffer from dermographism or pressure urticaria. Vibratory angioedema is diagnosed by holding a vibrating device such as a laboratory vortex machine against the forearm for four minutes. Speedy swelling of the whole forearm extending into the upper arm is also noted later. The principal treatment is avoidance of vibratory stimulants. Antihistamines have also been proven helpful.[

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 L50.4
Hospital discharge: ICD-9 7084
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 L50.4
Cause of death: ICD-9 7084
Cause of death: ICD-8 $!$

15

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

15

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Check minimum number of events None

15

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Include endpoints None

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L12_URTICA_VIBR

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L50
Name in latin Urticaria ex vibratione

Summary Statistics

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Key figures

All Female Male
Number of individuals 15 10 5
Unadjusted prevalence (%) 0.00 0.01 0.00
Mean age at first event (years) 47.71 42.91 57.32

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_URTICA_VIBR – Vibratory urticaria
GWS hits:

Survival analyses between endpoints

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Plot

before Vibratory urticaria
after Vibratory urticaria

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Vibratory urticaria

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