Gonarthrosis,primary

M13_ARTHROSIS_KNEE_PRIM_ICD10

No definition available.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 M17.0, M17.1
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 M17.0, M17.1
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

36255

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

36255

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Check minimum number of events None

36255

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Include endpoints None

36255

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M13_ARTHROSIS_KNEE_PRIM_ICD10

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF3

Summary Statistics

Key figures

All Female Male
Number of individuals 36255 21614 14641
Unadjusted prevalence (%) 10.19 10.89 9.30
Mean age at first event (years) 60.76 60.47 61.18

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.23 [1.09, 1.39] 9.2e-4 3221
15 years 0.01 1.00 [0.90, 1.12] 9.3e-1 1808
5 years 0.00 1.34 [1.20, 1.49] 1.9e-7 673
1 year 0.00 1.37 [1.12, 1.67] 2.4e-3 124

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: M13_ARTHROSIS_KNEE_PRIM_ICD10 – Gonarthrosis,primary
GWS hits:

Survival analyses between endpoints

Plot

before Gonarthrosis,primary
after Gonarthrosis,primary

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Drugs most likely to be purchased after Gonarthrosis,primary