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Arthrosis

DOID EFO MESH SNOMED PheWeb

M13_ARTHROSIS

Hemarthrosis: Bleeding into the joints. It may arise from trauma or spontaneously in patients with hemophilia.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 M15-M19
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 M15-M19
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

64664

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

64664

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Check minimum number of events None

64664

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Include endpoints

66730

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M13_ARTHROSIS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 66730 38585 28145
Unadjusted prevalence (%) 18.76 19.45 17.88
Mean age at first event (years) 59.17 58.93 59.51

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.19 [1.08, 1.32] 4.7e-4 6877
15 years 0.01 0.90 [0.83, 0.97] 1.1e-2 3414
5 years 0.00 1.40 [1.29, 1.52] 2.7e-16 1528
1 year 0.00 1.74 [1.52, 1.99] 2.2e-15 351

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_ARTHROSIS – Arthrosis
GWS hits: 47

Survival analyses between endpoints

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Plot

before Arthrosis
after Arthrosis

loading spinner Loading survival analyses plot