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Cervicocranial syndrome

DOID EFO MESH SNOMED PheWeb

M13_CERVICOCRANSDR

Barre-Lieou syndrome: A syndrome that involves occipital head aches, nystagmus on head movement, tinnitus, spasms, blurred vision, corneal hyperaesthesia, and corneal ulcers.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 M53.0
Hospital discharge: ICD-9 7232
Hospital discharge: ICD-8 7281
Cause of death: ICD-10 M53.0
Cause of death: ICD-9 7232
Cause of death: ICD-8 7281

2785

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

2772

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Check minimum number of events None

2772

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Include endpoints None

2772

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M13_CERVICOCRANSDR

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M53
Name in latin Syndroma cervicocraniale

Summary Statistics

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Key figures

All Female Male
Number of individuals 2772 1955 817
Unadjusted prevalence (%) 0.78 0.99 0.52
Mean age at first event (years) 52.65 51.72 54.87

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.74 [1.10, 2.76] 1.8e-2 185
15 years 0.01 1.29 [0.87, 1.92] 2.1e-1 89
5 years 0.00 1.98 [1.33, 2.95] 7.5e-4 39
1 year 0.00 3.26 [1.76, 6.04] 1.7e-4 12

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_CERVICOCRANSDR – Cervicocranial syndrome
GWS hits:

Survival analyses between endpoints

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Plot

before Cervicocranial syndrome
after Cervicocranial syndrome

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Drugs most likely to be purchased after Cervicocranial syndrome

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