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Diseases of the musculoskeletal system and connective tissue

PheWeb

M13_MUSCULOSKELETAL

No definition available.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 M00-M99, M90.6*C40.99, M90.6*C41.99
Cause of death: ICD-10 M00-M99, M90.6*C40.99, M90.6*C41.99

188630

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

188630

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Check minimum number of events None

188630

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Include endpoints

200471

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M13_MUSCULOSKELETAL

Extra metadata

Level in the ICD hierarchy 1
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 200471 114577 85894
Unadjusted prevalence (%) 56.35 57.75 54.58
Mean age at first event (years) 46.93 45.35 49.04

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.32 [1.23, 1.41] 4.5e-15 19723
15 years 0.01 0.96 [0.90, 1.03] 2.5e-1 8846
5 years 0.00 1.51 [1.41, 1.60] 2.7e-37 3740
1 year 0.00 3.17 [2.85, 3.52] <1e-100 1428

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_MUSCULOSKELETAL – Diseases of the musculoskeletal system and connective tissue
GWS hits:

Survival analyses between endpoints

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Plot

before Diseases of the musculoskeletal system and connective tissue
after Diseases of the musculoskeletal system and connective tissue

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Drugs most likely to be purchased after Diseases of the musculoskeletal system and connective tissue

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