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Reactive arthropathies

DOID EFO MESH SNOMED PheWeb

M13_REACTARTH

reactive arthritis: Reactive arthritis (ReA) is an autoimmune disorder belonging to the group of seronegative spondyloarthropathies and is characterized by the classic triad of arthritis, urethritis and conjunctivitis.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 M02, M03*
Hospital discharge: ICD-9 7111|7115|7118|713
Hospital discharge: ICD-8 71490
Cause of death: ICD-10 M02, M03*
Cause of death: ICD-9 7111|7115|7118|713
Cause of death: ICD-8 71490

4914

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

2608

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Check minimum number of events None

2608

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Include endpoints None

2608

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M13_REACTARTH

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 2608 1437 1171
Unadjusted prevalence (%) 0.73 0.72 0.74
Mean age at first event (years) 43.66 41.90 45.81

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.06 [1.30, 3.27] 2.1e-3 200
15 years 0.01 1.45 [0.94, 2.24] 9.0e-2 89
5 years 0.00 2.91 [1.95, 4.34] 1.8e-7 46
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_REACTARTH – Reactive arthropathies
GWS hits:

Survival analyses between endpoints

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Plot

before Reactive arthropathies
after Reactive arthropathies

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Reactive arthropathies

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