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Pre-eclampsia superimposed on chronic hypertension

DOID EFO MESH SNOMED PheWeb

O15_PREECLAMPS_CHRONIC_HYPERT

hypertension: Persistently high systemic arterial blood pressure. Based on multiple readings (blood pressure determination), hypertension is currently defined as when systolic pressure is consistently greater than 140 mm Hg or when diastolic pressure is consistently 90 mm Hg or more.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule

Sex only females

198506

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Check conditions None

198506

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Filter registries

Hospital Discharge: ICD-10 O11
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 O11
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

137

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

137

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Check minimum number of events None

137

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Include endpoints None

137

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O15_PREECLAMPS_CHRONIC_HYPERT

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF3
Parent code in ICD-10 O10-O16
Name in latin Hypertensio prae-existens cum proteinuria superposita

Summary Statistics

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Key figures

All Female Male
Number of individuals 137 137 -
Unadjusted prevalence (%) 0.04 0.07 -
Mean age at first event (years) 33.80 33.80 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: O15_PREECLAMPS_CHRONIC_HYPERT – Pre-eclampsia superimposed on chronic hypertension
GWS hits:

Survival analyses between endpoints

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Plot

before Pre-eclampsia superimposed on chronic hypertension
after Pre-eclampsia superimposed on chronic hypertension

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Drugs most likely to be purchased after Pre-eclampsia superimposed on chronic hypertension

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