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Postmenopausal osteoporosis with pathological fracture

MESH PheWeb

OSTPOPATFRCTURE_POSTEMENO

No definition available.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule

Sex only females

198506

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Check conditions None

198506

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Filter registries

Hospital Discharge: ICD-10 M80.0
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 M80.0
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

1205

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1205

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Check minimum number of events None

1205

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Include endpoints None

1205

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OSTPOPATFRCTURE_POSTEMENO

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 M80
Name in latin Osteoporosis postmenopausalis cum fractura pathologica

Summary Statistics

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Key figures

All Female Male
Number of individuals 1205 1205 -
Unadjusted prevalence (%) 0.34 0.61 -
Mean age at first event (years) 71.99 71.99 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.10 5.69 [4.45, 7.29] 1.5e-43 224
15 years 0.01 1.75 [1.32, 2.31] 8.0e-5 68
5 years 0.01 3.74 [2.78, 5.02] 2.3e-18 99
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: OSTPOPATFRCTURE_POSTEMENO – Postmenopausal osteoporosis with pathological fracture
GWS hits: 2

Survival analyses between endpoints

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Plot

before Postmenopausal osteoporosis with pathological fracture
after Postmenopausal osteoporosis with pathological fracture

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Drugs most likely to be purchased after Postmenopausal osteoporosis with pathological fracture

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