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Osteopathies and chondropathies

DOID EFO MESH SNOMED PheWeb

M13_OSTEOCHONDRO

secondary hypertrophic osteoarthropathy: Symmetrical osteitis of the four limbs, chiefly localized to the phalanges and the terminal epiphyses of the long bones of the forearm and leg, sometimes extending to the proximal ends of the limbs and the flat bones, and accompanied by dorsal kyphosis and joint involvement. It is often secondary to chronic conditions of the lungs and heart. (Dorland, 27th ed)

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 M80-M94, M90.6*C40.99, M90.6*C41.99
Cause of death: ICD-10 M80-M94, M90.6*C40.99, M90.6*C41.99

15328

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

15328

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Check minimum number of events None

15328

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Include endpoints

17328

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M13_OSTEOCHONDRO

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 17328 10846 6482
Unadjusted prevalence (%) 4.87 5.47 4.12
Mean age at first event (years) 52.98 54.61 50.24

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 3.60 [3.02, 4.27] 9.4e-48 2256
15 years 0.01 1.54 [1.31, 1.82] 2.4e-7 699
5 years 0.01 4.36 [3.79, 5.01] 3.0e-94 818
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_OSTEOCHONDRO – Osteopathies and chondropathies
GWS hits: 2

Survival analyses between endpoints

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Plot

before Osteopathies and chondropathies
after Osteopathies and chondropathies

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Osteopathies and chondropathies

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