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Left ventricular outflow tract obstruction, narrow definition

PheWeb

Q17_LVOTO_NARROW

No definition available.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 Q23, Q24.4, Q25.1, Q25.20, Q25.3, Q25.40
Hospital discharge: ICD-9 7463A|7464A|7463D|7465A|7466A|7467A|7468X|7463X|7471A|7472B|7471B
Hospital discharge: ICD-8 $!$
Hospital discharge: excluded ICD-10 Q90|Q91|Q92|Q93|Q96|Q8780|Q8781|Q8782|Q8783|Q8784|Q8786|Q8788|Q85|Q796|Q874|Q875
Hospital discharge: excluded ICD-9 758|7595|75683
Cause of death: ICD-10 Q23, Q24.4, Q25.1, Q25.20, Q25.3, Q25.40
Cause of death: ICD-9 7463A|7464A|7463D|7465A|7466A|7467A|7468X|7463X|7471A|7472B|7471B
Cause of death: ICD-8 $!$
Cause of death: excluded ICD-10 Q90|Q91|Q92|Q93|Q96|Q8780|Q8781|Q8782|Q8783|Q8784|Q8786|Q8788|Q85|Q796|Q874|Q875
Cause of death: excluded ICD-9 758|7595|75683

1148

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1148

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Check minimum number of events None

1148

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Include endpoints None

1148

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Q17_LVOTO_NARROW

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF7

Summary Statistics

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Key figures

All Female Male
Number of individuals 1148 420 728
Unadjusted prevalence (%) 0.32 0.21 0.46
Mean age at first event (years) 40.90 36.83 43.24

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 3.47 [1.60, 7.53] 1.7e-3 60
15 years 0.01 1.80 [0.82, 3.95] 1.4e-1 22
5 years 0.01 4.34 [2.20, 8.56] 2.3e-5 16
1 year 0.00 14.67 [6.90, 31.16] 2.8e-12 11

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: Q17_LVOTO_NARROW – Left ventricular outflow tract obstruction, narrow definition
GWS hits: 1

Survival analyses between endpoints

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Plot

before Left ventricular outflow tract obstruction, narrow definition
after Left ventricular outflow tract obstruction, narrow definition

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Left ventricular outflow tract obstruction, narrow definition

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