Systemic sclerosis, icd10

SYSTSCLE_ICD10

No definition available.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 M34
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 M34
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

549

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

549

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Check minimum number of events None

549

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Include endpoints None

549

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SYSTSCLE_ICD10

Extra metadata

First used in FinnGen datafreeze DF3
Parent code in ICD-10 M30-M36
Name in latin Sclerosis systemica

Summary Statistics

Key figures

All Female Male
Number of individuals 549 450 99
Unadjusted prevalence (%) 0.15 0.23 0.06
Mean age at first event (years) 55.17 55.06 55.66

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.10 6.01 [3.17, 11.40] 4.1e-8 52
15 years 0.01 2.03 [0.95, 4.31] 6.6e-2 14
5 years 0.01 6.69 [2.91, 15.34] 7.3e-6 20
1 year 0.00 18.51 [7.86, 43.56] 2.4e-11 11

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: SYSTSCLE_ICD10 – Systemic sclerosis, icd10
GWS hits:

Survival analyses between endpoints

Plot

before Systemic sclerosis, icd10
after Systemic sclerosis, icd10

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Drugs most likely to be purchased after Systemic sclerosis, icd10