Diseases of appendix

K11_APPENDIX

appendicitis: Acute inflammation of the vermiform appendix.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 K35-K38
Cause of death: ICD-10 K35-K38

13882

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

13882

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Check minimum number of events None

13882

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Include endpoints

28553

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K11_APPENDIX

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 28553 15546 13007
Unadjusted prevalence (%) 8.03 7.84 8.26
Mean age at first event (years) 34.23 32.33 36.50

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.10 [0.94, 1.29] 2.2e-1 1798
15 years 0.01 0.87 [0.76, 1.00] 4.5e-2 768
5 years 0.00 1.18 [1.01, 1.37] 3.6e-2 260
1 year 0.00 2.11 [1.66, 2.69] 1.4e-9 83

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: K11_APPENDIX – Diseases of appendix
GWS hits:

Survival analyses between endpoints

Plot

before Diseases of appendix
after Diseases of appendix

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Drugs most likely to be purchased after Diseases of appendix