Acute appendicitis, with complications

APPENDACUT_COMPLIC

appendicitis: Acute inflammation of the vermiform appendix.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 K35.0, K35.1
Hospital discharge: ICD-9 540[0-1]
Hospital discharge: ICD-8 540
Hospital discharge: excluded ICD-8 54090|54099
Cause of death: ICD-10 K35.0, K35.1
Cause of death: ICD-9 540[0-1]
Cause of death: ICD-8 540
Cause of death: excluded ICD-8 54090|54099

10526

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

6250

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Check minimum number of events None

6250

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Include endpoints None

6250

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APPENDACUT_COMPLIC

Extra metadata

First used in FinnGen datafreeze DF3

Summary Statistics

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Key figures

All Female Male
Number of individuals 6250 2966 3284
Unadjusted prevalence (%) 1.76 1.49 2.09
Mean age at first event (years) 36.40 34.04 38.53

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.86 [0.63, 1.18] 3.6e-1 663
15 years 0.00 0.73 [0.56, 0.95] 1.8e-2 291
5 years 0.00 1.09 [0.84, 1.43] 5.0e-1 106
1 year 0.00 2.38 [1.67, 3.40] 1.9e-6 41

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: APPENDACUT_COMPLIC – Acute appendicitis, with complications
GWS hits: 2

Survival analyses between endpoints

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Plot

before Acute appendicitis, with complications
after Acute appendicitis, with complications

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Acute appendicitis, with complications

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