Appendicitis, broad definition

APPENDICITIS_BROAD

appendicitis: Acute inflammation of the vermiform appendix.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries None

0

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Check pre-conditions, main-only, mode, ICD version None

0

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Check minimum number of events None

0

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Include endpoints

28332

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APPENDICITIS_BROAD

Extra metadata

First used in FinnGen datafreeze DF3

Summary Statistics

Key figures

All Female Male
Number of individuals 28332 15394 12938
Unadjusted prevalence (%) 7.96 7.76 8.22
Mean age at first event (years) 34.21 32.29 36.49

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.04 [0.89, 1.21] 6.3e-1 1777
15 years 0.01 0.82 [0.71, 0.94] 4.3e-3 761
5 years 0.00 1.10 [0.94, 1.28] 2.6e-1 256
1 year 0.00 1.95 [1.53, 2.50] 8.7e-8 82

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: APPENDICITIS_BROAD – Appendicitis, broad definition
GWS hits: 12

Survival analyses between endpoints

Plot

before Appendicitis, broad definition
after Appendicitis, broad definition

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Drugs most likely to be purchased after Appendicitis, broad definition