Brain astrocytoma

C3_ASTROCYTOMA

astrocytoma: A glial tumor of the brain or spinal cord showing astrocytic differentiation. It includes the following clinicopathological entities: pilocytic astrocytoma, diffuse astrocytoma, anaplastic astrocytoma, pleomorphic xanthoastrocytoma, subependymal giant cell astrocytoma, and glioblastoma.

Endpoint definition

FinnGen phenotype data

356077 individuals

diagram downward connector

Apply sex-specific rule None

356077

diagram downward connector
diagram bullet

Check conditions

HLP_C3_ASTROCYTOMA

62

diagram downward connector
diagram bullet

Filter registries

Cause of death: ICD-10 C71
Cause of death: ICD-9 191
Cause of death: ICD-8 191
Cancer registry: Topography ICD-O-3 C71
Cancer registry: Morphology ICD-O-3 9400
Cancer registry: Behaviour codes 3

62

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions C.O.D: 10, 8, 9

62

diagram downward connector

Check minimum number of events None

62

diagram downward connector
diagram bullet diagram downward connector

Include endpoints

62

diagram downward connector
C3_ASTROCYTOMA

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF8

Summary Statistics

Key figures

All Female Male
Number of individuals 62 23 39
Unadjusted prevalence (%) 0.02 0.01 0.02
Mean age at first event (years) 42.56 42.83 42.40

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: C3_ASTROCYTOMA – Brain astrocytoma
GWS hits:

Survival analyses between endpoints

Plot

before Brain astrocytoma
after Brain astrocytoma

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Brain astrocytoma