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Crohn's disease of large intestine

DOID EFO MESH PheWeb

CHRONLARGE

Crohn's colitis: Crohn's disease affecting the colon.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 K50.1
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 K50.1
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

1444

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1444

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Check minimum number of events None

1444

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Include endpoints None

1444

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CHRONLARGE

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 K50
Name in latin Colitis regionalis

Summary Statistics

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Key figures

All Female Male
Number of individuals 1444 812 632
Unadjusted prevalence (%) 0.41 0.41 0.40
Mean age at first event (years) 43.24 42.02 44.82

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.30 [0.56, 3.01] 5.4e-1 65
15 years 0.01 0.90 [0.37, 2.18] 8.2e-1 32
5 years 0.00 1.48 [0.67, 3.27] 3.4e-1 14
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: CHRONLARGE – Crohn's disease of large intestine
GWS hits: 3

Survival analyses between endpoints

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Plot

before Crohn's disease of large intestine
after Crohn's disease of large intestine

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Crohn's disease of large intestine

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