Inflammatory bowel disease

K11_IBD

inflammatory bowel disease: A spectrum of small and large bowel inflammatory diseases of unknown etiology. It includes Crohn's disease, ulcerative colitis, and colitis of indeterminate type.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries None

0

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Check pre-conditions, main-only, mode, ICD version None

0

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Check minimum number of events None

0

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Include endpoints

10311

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K11_IBD

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Inflammatory bowel disease based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 10311 5476 4835
Unadjusted prevalence (%) 2.90 2.76 3.07
Mean age at first event (years) 42.03 40.02 44.30

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.52 [1.07, 2.15] 1.8e-2 801
15 years 0.01 1.06 [0.81, 1.38] 6.9e-1 322
5 years 0.00 2.17 [1.73, 2.73] 3.0e-11 180
1 year 0.00 5.64 [4.30, 7.40] 1.1e-35 88

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: K11_IBD – Inflammatory bowel disease
GWS hits:

Survival analyses between endpoints

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Plot

before Inflammatory bowel disease
after Inflammatory bowel disease

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Drugs most likely to be purchased after Inflammatory bowel disease

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