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Noninfective enteritis and colitis

DOID EFO MESH SNOMED PheWeb

K11_ENERCOLNONINF

ulcerative colitis: An inflammatory bowel disease involving the mucosal surface of the large intestine and rectum. It may present with an acute or slow onset and follows an intermittent or continuous course. Signs and symptoms include abdominal pain, diarrhea, fever, weight loss, and intestinal hemorrhage.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 K50-K52
Cause of death: ICD-10 K50-K52

13982

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

13982

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Check minimum number of events None

13982

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Include endpoints

15709

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K11_ENERCOLNONINF

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Similar endpoints

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Summary Statistics

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Key figures

All Female Male
Number of individuals 15709 8721 6988
Unadjusted prevalence (%) 4.42 4.40 4.44
Mean age at first event (years) 44.68 43.04 46.73

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.34 [2.02, 2.71] 8.9e-30 1665
15 years 0.01 1.24 [1.08, 1.43] 2.9e-3 621
5 years 0.00 2.59 [2.26, 2.96] 5.7e-43 423
1 year 0.00 9.01 [7.65, 10.60] <1e-100 298

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: K11_ENERCOLNONINF – Noninfective enteritis and colitis
GWS hits: 25

Survival analyses between endpoints

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Plot

before Noninfective enteritis and colitis
after Noninfective enteritis and colitis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Noninfective enteritis and colitis

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