Other Chron's disease

CHRONOTH

ileocolitis: Ileocolitis or ileal Crohn's is the most common type of Crohn's disease. It affects both the ileum (small intestine) and the colon.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 K50.8
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 K50.8
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

1869

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1869

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Check minimum number of events None

1869

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Include endpoints None

1869

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CHRONOTH

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 K50
Name in latin Alis morbus Crohn specificatus

Summary Statistics

Key figures

All Female Male
Number of individuals 1869 1038 831
Unadjusted prevalence (%) 0.53 0.52 0.53
Mean age at first event (years) 42.53 41.63 43.64

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 2.78 [1.63, 4.74] 1.8e-4 62
15 years 0.01 1.84 [1.06, 3.19] 3.1e-2 31
5 years 0.00 2.89 [1.47, 5.65] 2.0e-3 15
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: CHRONOTH – Other Chron's disease
GWS hits: 6

Survival analyses between endpoints

Plot

before Other Chron's disease
after Other Chron's disease

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Drugs most likely to be purchased after Other Chron's disease