Crohn's disease of small interstine

CHRONSMALL

No definition available.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 K50.0
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 K50.0
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

1819

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1819

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Check minimum number of events None

1819

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Include endpoints None

1819

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CHRONSMALL

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 K50
Name in latin Morbus Crohn intestini tenuis

Summary Statistics

Key figures

All Female Male
Number of individuals 1819 1031 788
Unadjusted prevalence (%) 0.51 0.52 0.50
Mean age at first event (years) 44.70 42.77 47.24

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 2.84 [1.58, 5.09] 4.7e-4 73
15 years 0.01 1.73 [1.02, 2.93] 4.3e-2 29
5 years 0.01 4.01 [2.37, 6.79] 2.1e-7 21
1 year 0.00 13.33 [7.17, 24.78] 2.7e-16 14

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: CHRONSMALL – Crohn's disease of small interstine
GWS hits: 8

Survival analyses between endpoints

Plot

before Crohn's disease of small interstine
after Crohn's disease of small interstine

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Drugs most likely to be purchased after Crohn's disease of small interstine