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Amyloidosis, other/unspecified

DOID EFO MESH SNOMED PheWeb

E4_AMYLNAS

amyloidosis: A disorder characterized by the localized or diffuse accumulation of amyloid protein in various anatomic sites. It may be primary, due to clonal plasma cell proliferations; secondary, due to long standing infections, chronic inflammatory disorders, or malignancies; or familial. It may affect the nerves, skin, tongue, joints, heart, liver, spleen, kidneys and adrenal glands.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 E85[8-9]
Hospital discharge: ICD-9 2773
Hospital discharge: ICD-8 27699
Cause of death: ICD-10 E85[8-9]
Cause of death: ICD-9 2773
Cause of death: ICD-8 27699

694

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

377

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Check minimum number of events None

377

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Include endpoints None

377

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E4_AMYLNAS

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 377 191 186
Unadjusted prevalence (%) 0.11 0.10 0.12
Mean age at first event (years) 62.36 59.36 65.44

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_AMYLNAS – Amyloidosis, other/unspecified
GWS hits: 9

Survival analyses between endpoints

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Plot

before Amyloidosis, other/unspecified
after Amyloidosis, other/unspecified

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Amyloidosis, other/unspecified

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